N-去乙基阿莫地喹（盐酸盐）是阿莫地喹的主要生物活性代谢物。
| Cas No. | 79049-30-2 |
| 别名 | 去乙基阿莫地喹盐酸盐 |
| Canonical SMILES | OC(C=C1)=C(CNCC)C=C1NC2=CC=NC3=C2C=CC(Cl)=C3.Cl.Cl |
| 分子式 | C18H18ClN3O•2HCl |
| 分子量 | 400.7 |
| 溶解度 | DMSO: soluble,Methanol: Soluble,Water: Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1]. References:
[1]. Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82. |
