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Deriglidole(SL 86-0715)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Deriglidole(SL 86-0715)图片
CAS NO:122830-14-2
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Deriglidole (SL 86-0715) 是一种外周肾上腺素受体拮抗剂,对 α2-肾上腺素受体具有高亲和力。
Cas No.122830-14-2
别名德格列哚,SL 86-0715
Canonical SMILESCCCC1(C2=NCCN2)N3C4=C(C=CC=C4CC3)C1
分子式C16H21N3
分子量255.36
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Deriglidole is a peripheral adrenoceptor antagonist with a high affinity for α2-adrenoceptors.

Deriglidole is a selective α2-receptor inhibitor. Deriglidole inhibits [3H]Clonidine and [3H]Idazoxan but not [3H]Prazosin binding to rat cortical and human platelet α2-adrenoceptors and is more selective than Idazoxan for peripheral receptors[1].

[1]. Natali A, et al. Effects of acute alpha 2-blockade on insulin action and secretion in humans. Am J Physiol. 1998 Jan;274(1 Pt 1):E57-64.

 
 
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