化学性质
Storage | Store at -20°C |
M.Wt | 445.38 |
Cas No. | 324523-20-8 |
Formula | C24H26Cl2N2O2 |
Synonyms | NPS2143 hydrochloride;NPS 2143 hydrochloride |
Solubility | ≥44.5 mg/mL in DMSO; insoluble in H2O; ≥11.43 mg/mL in EtOH with gentle warming and ultrasonic |
Chemical Name | 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile;hydrochloride |
Canonical SMILES | CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O.Cl |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
NPS-2143 is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.NPS-2143 is useful for treatment of osteoporosis;