N-Acetyl-D-cysteine 具有抗氧化活性,通过与巯基反应清除 ROS,但不能进入谷胱甘肽代谢途径。
Cas No. | 26117-28-2 |
别名 | N-乙酰基-D-半胱氨酸 |
Canonical SMILES | SC[C@H](C(O)=O)NC(C)=O |
分子式 | C5H9NO3S |
分子量 | 163.19 |
溶解度 | Water: 250 mg/mL (1531.96 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway[1]. [1]. Maika Deffieu, et al. Glutathione Participates in the Regulation of Mitophagy in Yeast.J Biol Chem. 2009 May 29;284(22):14828-37.
[2]. B K Wong,et al. Selective Effects of N-acetylcysteine Stereoisomers on Hepatic Glutathione and Plasma Sulfate in Mice. Toxicol Appl Pharmacol
[3]. Suparna Qanungo, et al. N-Acetyl-L-cysteine Enhances Apoptosis Through Inhibition of Nuclear factor-kappaB in Hypoxic Murine Embryonic Fibroblasts. J Biol Chem |