AHR antagonist 2 是一种有效的芳香烃受体 (AHR) 拮抗剂，对人和小鼠的 IC50 值分别为 0.885，2.03 nM，详情请参见专利 WO2019101641A1，example 1。
| Cas No. | 2338747-54-7 |
| Canonical SMILES | O=C(C1=NC(C2=CC=CN=C2)=NC(C3=CC=C(OC(F)(F)F)C=C3)=C1)N[C@@H](C)CO |
| 分子式 | C20H17F3N4O3 |
| 分子量 | 418.37 |
| 溶解度 | DMSO: 250 mg/mL (597.56 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | AHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1, with IC50s of 0.885 and 2.03 nM for human and mouse AhR[1]. [1]. Julien LEFRANC, et al. 2-hetarylpyrimidine-4-carboxamides as aryl hydrocarbon receptor anatgonists. WO2019101641A1. |
