化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 475.54 |
Cas No. | 1204707-73-2 |
Formula | C18H23F2N5O4S2 |
Synonyms | SRT 3190;SRT-3190 |
Solubility | ≥47.6 mg/mL in DMSO; insoluble in H2O; ≥99.4 mg/mL in EtOH with ultrasonic |
Chemical Name | N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2S,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide |
Canonical SMILES | CC(C(CO)O)NC1=CC(=NC(=N1)SCC2=C(C(=CC=C2)F)F)NS(=O)(=O)N3CCC3 |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3.