Cefpodoxime

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Cefpodoxime

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

80210-62-4

Cefpodoxime acid
R 3763

Cefpodoxime (Cefpodoxime acid) 是一种对革兰氏阳性和革兰氏阴性细菌有效的抗生素。Cefpodoxime 对微生物种群中的大多数细胞具有抑制作用。Cefpodoxime 可用于急性中耳炎、鼻窦炎和口咽炎的研究。

生物活性

Cefpodoxime (Cefpodoxime acid) is a potentantibioticactive against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research^[1]^[2].

体外研究
(In Vitro)

Cefpodoxime (Cefpodoxime acid) inhibits gram-negative anaerobic rods (Bacteroidaceae) with MIC values of 0.125-4 mg/L. Cefpodoxime inhibitsVeillonella parvulawith MIC values of 0.25-8 mg/L. Cefpodoxime inhibitsPeptostreptococcus micros,Peptostreptococcus asaccharolyticusandRuminococcus bromiiwith MIC values of<2 mgl^[1].
Cefpodoxime (Cefpodoxime acid) inhibits bacterial populations ofS. pneumoniaeandS. pyogenes.cfu^[2].

体内研究
(In Vivo)

Cephalosporins (2.5-50 mg/kg; p.o.; every 8 hours; for 48 hours) have good curative effect in mice^[3].

Animal Model:	Female Swiss CD1 mice^[3]
Dosage:	2.5, 5, 10, 25, 40 and 50 mg/kg
Administration:	Oral administration; every 8 hours; for 48 hours
Result:	Efficacy was obtained with values of >350.

Clinical Trial

分子量

427.46

性状

Solid

Formula

C₁₅H₁₇N₅O₆S₂

CAS 号

80210-62-4

中文名称

头孢泊肟酯EP杂质A (Cefpodoxime Acid)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

DMSO : 250 mg/mL(584.85 mM;Need ultrasonic)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	2.3394 mL	11.6970 mL	23.3940 mL
5 mM	0.4679 mL	2.3394 mL	4.6788 mL
10 mM	0.2339 mL	1.1697 mL	2.3394 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。