EBOV-GP-IN-1 (Compound 28) 是一种有效的Ebola进入抑制剂,对埃博拉病毒包膜糖蛋白(EBOV-GP)的IC50为 0.05 μM。
生物活性 | EBOV-GP-IN-1 (Compound 28) is a potentEbolaentry inhibitor with anIC50of 0.05 μM against Ebola virus envelopeglycoprotein(EBOV-GP)[1]. |
IC50& Target | IC50: 0.05 μM (EBOV-GP), 3.02 μM (VSV-G)[1] |
体外研究 (In Vitro) | EBOV-GP-IN-1 (Compound 28) (0-80 μM, 2 days) shows cytotoxicity with a CC50of 5.10 ± 1.56 μM for Huh7 cells in pseudotyped virus assay[1]. EBOV-GP-IN-1 exhibits remarkable selectivity between EBOV-GP and VSV-G (vesicular stomatitis virus glycoprotein) (Spec. Index = 58)[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |