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SBFI AM
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
SBFI AM图片
CAS NO:129423-53-6
包装:1mg
市场价:5972元

SBFI AM 是一种 Na+ 选择性荧光指示剂。
Cas No.129423-53-6
别名Sodium-binding Benzofuran Isophthalate Acetoxymethyl ester
化学名4,4’-[1,4,10-trioxa-7,13-diazacyclopentadecane-7,13-diylbis(5-methoxy-6,2-benzofurandiyl)]bis-1,3-benzenedicarboxylic acid 1,1’,3,3’-tetrakis[(acetyloxy)methyl] ester
Canonical SMILESO=C(OCOC(C)=O)C(C=C1)=CC(C(OCOC(C)=O)=O)=C1C2=CC(C=C3OC)=C(O2)C=C3N4CCOCCOCCN(C5=C(OC)C=C(C=C(C6=C(C(OCOC(C)=O)=O)C=C(C(OCOC(C)=O)=O)C=C6)O7)C7=C5)CCOCC4
分子式C56H58N2O23
分子量1127.1
溶解度Methanol: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

SBFI AM is a membrane-permeant, fluorescent Na+ indicator dye. It is selective for Na+ over K+ with Kd values of 20 and 120 mM for these ions, respectively. [1]Increasing concentration of Na+ increases the ratio of excitation efficiency at 330-345 nm to that at 370-390 nm with emission collected at 450-550 nm. [1] Therefore, ratio fluorometry and imaging can be performed with the same wavelengths. SBF AM is suitable for single intracellular dye injection and is typically used for high-resolution measurements of Na+ concentration in intact tissue through two-photon confocal imaging.[2]

Reference:
[1]. Minta, A., and Tsien, R.Y. Fluorescent indicators for cytosolic sodium. The Journal of Biological Chemisty 264(32), 19449-19457 (1989).
[2]. Meier, S.D., Kovalchuk, Y., and Rose, C.R. Properties of the new fluorescent Na+ indicator CoroNa Green: Comparison with SBFI and confocal Na+ imaging. Journal of Neuroscience Methods 155(2), 251-259 (2006).

 
 
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