牡丹素（氯化物）是一种 O-甲基化的花青素，可作为主要植物色素，赋予牡丹等花卉以及浆果和蔬菜以紫红色的色调。 Peonidin (chloride) 在体外对癌细胞具有化学预防和抗炎活性，可阻断 JB6 P+5 小鼠表皮细胞中的 COX-2 表达和转化。
| Cas No. | 134-01-0 |
| 别名 | 氯化芍药素,YGM-6 chloride |
| 化学名 | 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-benzopyrylium, monochloride |
| Canonical SMILES | OC1=CC(O)=C(C=C(O)C(C2=CC=C(O)C(OC)=C2)=[O+]3)C3=C1.[Cl-] |
| 分子式 | C16H13O6•Cl |
| 分子量 | 336.7 |
| 溶解度 | 16mg/mL in ethanol, 25mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Peonidin is an O-methylated anthocyanidin that functions as a primary plant pigment, endowing purplish-red hues to flowers such as the peony, from which it takes its name, as well as berries and vegetables. It has been shown to exhibit chemopreventive, as well as anti-inflammatory activities on cancer cells in vitro, blocking COX-2 expression and transformation in JB6 P+ mouse epidermal cells. [1] Reference:
[1]. Kwon, J.Y., Lee, K.W., Hur, H.J., et al. Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2. Ann.N.Y.Acad.Sci. 2007:1095, 513-520 (2007). |
