Bulevirtide (Myrcludex B; MyrB; Hepcludex) is a first-in-class entry inhibitor approved as an antiviral medication for the treatment of chronic hepatitis D. As a novel virion entry inhibitor, Bulevirtide blocks the virion's
hepatocyte pathway of entry, the hepatic sodium/taurocholate
cotransporting polypeptide (NTCP) receptor. In July 2020 bulevirtide was authorized for
use in the E.U. following a positive opinion by the European Medicines
Agency (EMA) for the treatment of chronic HDV infection in HDV
RNA-positive adult patients with compensated liver disease.
纯度:≥98%
CAS:2012558-47-1