ICy-Q 是一种醌氧化还原酶 1 (NQO-1) 激活的近红外 (NIR) 试剂,通过与 NQO-1 反应释放还原产物 ICy-OH。 ICy-OH 可通过诱导细胞焦亡 (pyroptosis) 途径选择性地诱导胰腺癌细胞死亡。ICy-Q 可以作为快速、准确地诊断术中病理切片的有效工具。
生物活性 | ICy-Q is a quinone oxidoreductase 1 (NQO-1)-activated near-infrared (NIR) reagent which can react with NQO-1 to release the reduction product ICy-OH. ICy-OH selectively induces pancreaticcancercell death through thepyroptosispathway. ICy-Q can be used as an effective tool for rapid and accurate diagnosis of intraoperative pathological sections[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |