Ac-FEID-CMK 是一种有效的斑马鱼特异性GSDMEb衍生肽抑制剂。Ac-FEID-CMK 可减轻感染性休克的死亡率和肾损伤。Ac-FEID-CMK 在体内可抑制焦亡，减轻败血性 AKI (急性肾损伤)。Ac-FEID-CMK 可抑制 caspy2 介导的非典型炎症小体通路。
| 生物活性 | Ac-FEID-CMK is a potent zebrafish-specificGSDMEb-derived peptideinhibitor.
Ac-FEID-CMK can attenuate the mortality and kidney injury during septic shock. Ac-FEID-CMK inhibitspyroptosisand attenuates septic AKI (acute kidney injury)in vivo. Ac-FEID-CMK can suppress the caspy2-mediated noncanonical inflammasome pathway[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
