MtTMPK-IN-3

立即咨询

MtTMPK-IN-3

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

MtTMPK-IN-3 (compound 25) 是一种有效的分支杆菌胸苷酸激酶 (MtbTMPK)抑制剂，IC₅₀为 0.12 μM。MtTMPK-IN-3 对MtbH37Rv 具有抑制活性 (MIC = 12.5 μM)。MtTMPK-IN-3 对人成纤维细胞 MRC-5 具有一定的细胞毒性 (EC₅₀= 12.5 μM)。MtTMPK-IN-3 可用于结核病的研究。

生物活性	MtTMPK-IN-3 (compound 25) is a potentMycobacterium tuberculosisthymidylate kinase (MtTMPK)inhibitor with anIC₅₀value of 0.12 μM. MtTMPK-IN-3 has inhibitory activity againstMtbH37Rv (MIC = 12.5 μM). MtTMPK-IN-3 exhibits certain cytotoxicity in human fibroblast cells MRC-5 (EC₅₀= 12.5 μM). MtTMPK-IN-3 can be used for researching tuberculosis^[1].
IC₅₀& Target	IC₅₀: 0.12 μM (MtbTMPK)^[1]
分子量	460.35
Formula	C₂₃H₂₃Cl₂N₃O₃
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.