Cas9-IN-2 是一种有效的Cas9抑制剂 (IC50=246 μM),通过与 apo-Cas9 结合来防止 Cas9:gRNA 复合物的形成,可应用于调节和控制 Cas9 的活性。
生物活性 | Cas9-IN-2 is a potentCas9inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications[1]. |
体外研究 (In Vitro) | Cas9-IN-1 (compound 2) (200 and 500 μM; overnight) helps theE. coliselection strain to survive SpyCas9-induced killing[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |