RSS0680

立即咨询

RSS0680

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2769753-48-0

RSS0680 (Example 22) 是一种靶向蛋白降解激酶的双功能化合物。RSS0680 降解 AAK1、CDK1、CDK16、CDK2、CDK4、CDK6、EIF2AK4、GAK、LATSl、LIMK2、MAPK6、MAPKAPK5、MARK2、MARK4、MKNK2、NEK9、RPS6KB1、SIK2、SNRK、STK17A、STK17B、STK35 和 WEEl。RSS0680 可用于研究异常激酶活性介导的疾病或紊乱。

生物活性

RSS0680 (Example 22) is a bifunctional compound targeted protein degradation of kinases. RSS0680 degradesAAK1,CDK1,CDK16,CDK2,CDK4,CDK6, EIF2AK4, GAK, LATSl,LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1,SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used for research of disease or disorder mediated by aberrant kinase activity^[1].

IC₅₀& Target

CDK1

CDK2

CDK4

CDK6

SIK2

CDK16/Cyclin Y

分子量

1021.32

Formula

C₅₂H₆₄N₁₀O₆S₃

CAS 号

2769753-48-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.