Dynamin IN-2 (compound 43)，一种Wiskostatin (HY-12534) 类似物，是一种有效的dynamin抑制剂，对dynamin I GTPase的IC50为 1.0 μM。Dynamin IN-2 还可阻断网格蛋白介导的内吞作用 (CME)，IC50为 9.5 μM。
| 生物活性 | DynaminIN-2 (compound 43), aWiskostatin(HY-12534) analogue, is a potentdynamininhibitor, with anIC50of 1.0 μM fordynaminI GTPase.DynaminIN-2 also blocks clathrin mediatedendocytosis(CME), with anIC50of 9.5 μM[1]. |
| IC50& Target | IC50: 1.0 ± 0.2 μM (dyn I GTPase), 9.5 ± 2.5 μM (CME)[1] |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
