Dynole 2

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Dynole 2–24

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1416313-72-8

包装与价格：

包装	价格(元)
5mg	询价
10mg	询价
25mg	询价
50mg	询价
100mg	询价

Dynole 2–24 是一种基于吲哚的dynamin GTPase抑制剂 (对 dynamin I的IC₅₀=0.56 μM)。Dynole 2–24 无毒，在体外和细胞内显示出增强的抗动力蛋白I和II的效力 (IC_50(CME)=1.9 μM)。Dynole 2–24 对 dynamin I的选择性为4.4倍。Dynole 2–24在网格蛋白介导的内吞作用的细胞抑制剂中具有活性。CME: Clathrin mediated endocytosis

生物活性	Dynole 2–24 is an indole-baseddynaminGTPaseinhibitor (IC₅₀=0.56 μM fordynaminI). Dynole 2–24 is nontoxic and shows increased potency againstdynaminI and II in vitro and in cells (IC_50(CME)=1.9 μM). Dynole 2–24 also shows 4.4-fold selectivity fordynaminI. Dynole 2–24 is active in-cell inhibitor of clathrin-mediated endocytosis^[1]. CME: Clathrin mediated endocytosis
分子量	371.60
Formula	C₂₄H₄₁N₃
CAS 号	1416313-72-8
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.