Lademirsen (SAR339375; RG-012) 是一种靶向miR-21并抑制其功能的寡核苷酸。Lademirsen 具有用于 Alport 肾病研究的潜力。
| 生物活性 | Lademirsen (SAR339375; RG-012) is a single stranded, chemically modified oligonucleotide that binds to and inhibits the function ofmiR-21. Lademirsen has the potential for Alport nephropathy research[1][2]. |
体内研究
(In Vivo) | Administration of Lademirsen (SAR339375; RG-012) to inhibit miR-21 leads to a slowed progression of renal fibrosis and an increased lifespan in Alport syndrome mouse models[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
