Tetraethylene glycol monotosylate 是一种可降解 (cleavable) 的基于酰基腙的 ADC linker,用于合成抗体偶联药物 (ADCs)。Tetraethylene glycol monotosylate 也可用作 PROTAC 的 Linker,可用于 PROTAC 的合成。
Cas No. | 77544-60-6 |
别名 | Tos-PEG4 |
分子式 | C15H24O7S |
分子量 | 348.41 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-basedADC linkerused in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |