CAS NO: | 39968-33-7 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 询价 |
25g | 询价 |
100g | 询价 |
coupling activator for racemization-free coupling in peptide synthesis
Cas No. | 39968-33-7 |
别名 | N-羟基-7-氮杂苯并三氮唑 |
化学名 | 3-hydroxytriazolo[4,5-b]pyridine |
Canonical SMILES | C1=CC2=C(N=C1)N(N=N2)O |
分子式 | C5H4N4O |
分子量 | 136.11 |
溶解度 | ≥ 6.8mg/mL in DMSO, ≥ 9.29 mg/mL in EtOH with ultrasonic, ≥ 3.62 mg/mL in Water with ultrasonic |
储存条件 | Desiccate at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | A coupling activator for racemization-free coupling in peptide synthesis; An additive for peptide segment coupling in in reducing the extent of configurational loss at the reactive carboxylic acid residue. Carpino L A etc. works demonstrated that the DIC/HOAt system is more effective in preserving configuration for peptide segment coupling than the analogous DIC/HOBt system in DMF and DCM. [1] Reference: |
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