Efflux inhibitor-1 (compound 2) 是吡唑啉 [1,5-a] 嘧啶外排抑制剂。Efflux inhibitor-1 在ABCG2/BCRP，ABCB1间选择性靶向ABCG2，IC50分别为 0.45 μM 和 2.17 μM。
| 生物活性 | Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets towardABCG2/BCRPoverABCB1withIC50s of 0.45 μM and 2.17 μM, respectively[1]. |
| IC50& Target | IC50: 0.45 μM (ABCG2/BCRP), 2.17 μM (ABCB1)[1] |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
