CALP2

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CALP2

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

261969-04-4

CALP2 是一种钙调蛋白 (CaM) 拮抗剂 (K_d为 7.9 μM)，以亲和力结合CaMEF-hand/Ca²⁺结合位点。CALP2 抑制CaM依赖性磷酸二酯酶 (phosphodiesterase) 活性并增加细胞内 Ca²⁺浓度。CALP2 有效抑制粘附和脱粒。CALP2 还是肺泡巨噬细胞的强激活剂。

生物活性	CALP2 is acalmodulin(CaM)antagonist ( (K_dof 7.9 μM)) with high affinity for binding to theCaMEF-hand/Ca²⁺-binding site. CALP2 inhibitsCaM-dependentphosphodiesteraseactivity and increases intracellular Ca²⁺concentrations. CALP2 potently inhibits of adhesion and degranulation. CALP2 is also a strong activator of alveolar macrophages^[1]^[2]^[3]^[4].
分子量	1357.70
Formula	C₆₈H₁₀₄N₁₄O₁₃S
CAS 号	261969-04-4
Sequence	Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-Val-Met-Val-Phe
Sequence Shortening	VKFGVGFKVMVF
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.