Gamma-secretase modulator 2是γ-secretase调节剂，可用于阿尔兹海默。
| Cas No. | 1093978-89-2 |
| 别名 | 6-氟-1,3,4,5-四氢-3-[4-[3-甲氧基-4-(4-甲基-1H-咪唑-1-基)苯基]-1H-1,2,3-三唑-1-基]-1-(2,2,2-三氟乙基)-2H-1-苯并-2-酮 |
| Canonical SMILES | O=C1N(C2=CC=CC(F)=C2CCC1N3N=NC(C4=CC(OC)=C(N5C=NC(C)=C5)C=C4)=C3)CC(F)(F)F |
| 分子式 | C25H22F4N6O2 |
| 分子量 | 514.47 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's diseaseIC50 value: Target: γ-secretaseγ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer's disease. |
