| CAS NO: | 1031336-60-3 |
| Cas No. | 1031336-60-3 |
| 别名 | 反式-4-[4-(7-氨基吡唑并[1,5-A]嘧啶-6-基)苯基]环己烷乙酸 |
| Canonical SMILES | NC1=C(C2=CC=C([C@H]3CC[C@H](CC(O)=O)CC3)C=C2)C=NC4=CC=NN41 |
| 分子式 | C20H22N4O2 |
| 分子量 | 350.41 |
| 溶解度 | DMSO: 66.67 mg/mL (190.26 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | ABT-046 is a potent, selective, and orally efficacious acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50= 8 nM)[1]. [1]. Yeh VS, et al. Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of Acyl-CoA: Diacylglycerol acyltransferase 1. J Med Chem. 2012 Feb 23;55(4):1751-1757. |
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