4-Methylesculetin 是一种可口服的天然香豆素衍生物，具有有效的抗氧化、抗炎活性。4-Methylesculetin 可抑制 myeloperoxidase 的活性，降低 IL-6 的水平
| Cas No. | 529-84-0 |
| 别名 | 4-甲基七叶亭 |
| Canonical SMILES | O=C1C=C(C)C2=CC(O)=C(O)C=C2O1 |
| 分子式 | C10H8O4 |
| 分子量 | 192.17 |
| 溶解度 | DMSO : 50 mg/mL (260.19 mM; Need ultrasonic); Water :< 0.1 mg/mL (insoluble) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 4-Methylesculetin is an orally active natural coumarin derivative, with potent anti-oxidant and anti-inflammatory activities. 4-Methylesculetin inhibits myeloperoxidase activity and reduces IL-6 level[1]. [1]. Witaicenis A, et al. 4-methylesculetin, a coumarin derivative, ameliorates dextran sulfate sodium-induced intestinal inflammation. Chem Biol Interact. 2018 Jan 25;280:59-63. |
