Rimeporide hydrochloride (EMD-87580 hydrochloride) 是一种有效的选择性Na+/H+交换泵 (NHE-1) 抑制剂。
| 生物活性 | Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of theNa+/H+exchanger (NHE-1). |
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体外研究
(In Vitro) | Blocking NHE-1 activity has been shown to decrease intracellular Na+and Ca2+overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
