NGR peptide

立即咨询

NGR peptide

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

651328-78-8

NGR peptide 是含有 Asn-Gly-Arg (NGR) 基序的肽。NGR peptide 与 APN/CD13 结合。NGR peptide 直接偶联成像剂，可用于肿瘤成像。

生物活性

NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging^[1]^[2].

IC₅₀& Target

CD13/aminopeptidase N (APN) receptor^[1]

体内研究
(In Vivo)

NGR peptide (20 mg/kg; i.v.) 可用作肿瘤成像和早期诊断的潜在 SPECT 试剂^[2]。

Animal Model:	4-6 weeks, BALB/c nude mice (HepG2 tumor model)^[2]
Dosage:	20 mg/kg
Administration:	I.v.
Result:	Blocked the tumor uptake for 99mTc-NGR.

分子量

608.69

Formula

C₂₀H₃₆N₁₀O₈S₂

CAS 号

651328-78-8

Sequence

Cys-Asn-Gly-Arg-Cys-Gly

Sequence Shortening

CNGRCG

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.