Edaglitazone is an agonist of peroxisome proliferator-activated receptor γ (PPARγ).
| Cas No. | 213411-83-7 |
| 别名 | 依格列宗 |
| Canonical SMILES | CC(OC(C1=CC=CC=C1)=N2)=C2CCOC3=C4C(SC=C4)=C(CC5SC(NC5=O)=O)C=C3 |
| 分子式 | C24H20N2O4S2 |
| 分子量 | 464.6 |
| 溶解度 | DMSO: 30 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Edaglitazone is an agonist of peroxisome proliferator-activated receptor γ (PPARγ). It activates PPARγ in a reporter assay using CV-1 cells expressing murine PPARγ2 when used at concentrations ranging from 0.1 to 1 μM. Edaglitazone (1, 5, and 25 μM) increases [3H]2-deoxyglucose transport in the presence and absence of insulin and increases glycogen synthesis in the presence of insulin in soleus muscle strips isolated from obese rats. |
