Juglone 是一种在黑胡桃 (Juglans regia) 中发现的黄色色素。
| Cas No. | 481-39-0 |
| 别名 | 胡桃醌; 5-Hydroxy-1,4-naphthalenedione |
| Canonical SMILES | O=C1C=CC(C2=CC=CC(O)=C21)=O |
| 分子式 | C10H6O3 |
| 分子量 | 174.2 |
| 溶解度 | DMSO: 10 mg/ml,Ethanol: 10 mg/ml |
| 储存条件 | 4°C, protect from light ,unstable in solution, ready to use. |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. It has allelopathic actions, suppressing growth, photosynthesis, and respiration in plants and other organisms, although some bacteria can metabolize juglone. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 µM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms. |
