Deoxyneocryptotanshinone

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CAS NO:

27468-20-8

脱氧基新隐丹参酮

Deoxyneocryptotanshinone 是一种天然丹参酮，是一种高亲和力的BACE1(Beta-secretase) 抑制剂，IC₅₀值为 11.53 μM。Deoxyneocryptotanshinone 显示出对蛋白酪氨酸磷酸酶 1B (PTP1B) 的剂量依赖性抑制作用，IC₅₀值为 133.5 μM。Deoxyneocryptotanshinone 可用于阿尔茨海默病研究。

生物活性	Deoxyneocryptotanshinone, a natural tanshinone, is a high affinityBACE1(Beta-secretase) inhibitor with anIC₅₀value of 11.53 μM. Deoxyneocryptotanshinone shows a promising dose-dependent inhibition ofprotein tyrosinephosphatase1B (PTP1B)with anIC₅₀value of 133.5 μM. Deoxyneocryptotanshinone can be used for Alzheimer's disease research^[1]^[2].
IC₅₀& Target	IC50: 11.53 μM (BACE1)^[1]and 133.5 μM (PTP1B)^[2]
分子量	298.38
Formula	C₁₉H₂₂O₃
CAS 号	27468-20-8
中文名称	脱氧基新隐丹参酮
结构分类	Terpenoids Diterpenoids
来源	Plants Compositae Hemistepta lyrata Plants Labiatae
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.