PSN 375963 hydrochloride

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CAS NO:

1781834-82-9

PSN 375963 hydrochloride 是一种有效的GPR119激动剂，对人和小鼠的EC₅₀分别为 8.4 和 7.9 μM。PSN 375963 hydrochloride 显示出与内源性油酰乙醇酰胺 (OEA) 相似的效力。

生物活性	PSN 375963 hydrochloride is a potentGPR119agonist, withEC₅₀s of 8.4 and 7.9 μM for human and mouseGPR119, respectively. PSN 375963 hydrochloride shows similar potency to the endogenous agonist oleoylethanolamide (OEA)^[1]^[2].
体外研究 (In Vitro)	The endogenous ligand OEA signals through GPR119 in a manner similar to glucagon-like peptide-1 (GLP-1) and its receptor with respect to insulin secretion, intracellular calcium and cAMP^[2].
分子量	321.84
Formula	C₁₇H₂₄ClN₃O
CAS 号	1781834-82-9
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.