(R)-MLT-985 (compound 11) 是一种有效的MALT1蛋白酶抑制剂，IC50为 3 nM。(R)-MLT-985 在 Jurkat 细胞中对 MALT1 依赖性 IL-2 的 IC50为 20 nM。(R)-MLT-985 抑制 ABC-DLBCL 细胞中的生长和异常 CARD11/BCL10/MALT1 复合物信号传导。
| 生物活性 | (R)-MLT-985 (compound 11) is a potentMALT1proteaseinhibitor with anIC50of 3 nM. (R)-MLT-985 has an IC50of 20 nM for MALT1-dependentIL-2production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells[1]. |
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
