PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC-based degrader of SKG3 (Serum/Glucocorticoid Regulated Kinase Family Member 3), inducing 50% degradation of endogenous SGK3 in 2 hours, with maximal
80% degradation occurred within 8 hours, accompanied by a loss of
phosphorylation of NDRG1 (an SGK3 substrate).
纯度:≥98%
CAS:2381320-35-8