AUTAC2 是一种FKBP12靶向自噬介导降解体 (AUTAC)。AUTAC2 包含一个 FBnG 和 SLF 部分，其中 SLF 与FKBP12 非共价结合。
| 生物活性 | AUTAC2 is aFKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12[1]. |
体外研究
(In Vitro) | AUTAC1 (1-100 μM, 24 h) silences endogenous FKBP12 in hela cells[1].
Western Blot Analysis[1] | Cell Line: | HeLa cells. | | Concentration: | 0-100 μM. | | Incubation Time: | 24 h. | | Result: | Silenced endogenous FKBP12. |
|
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
