FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 是 AUTAC4 的连接体。AUTAC4 含有一个 p-氟苄鸟嘌呤 (FBnG) 和一个苯基吲哚部分,可在 HeLa 细胞中诱导 K63 连接的多泛素化和细胞线粒体的降解。
生物活性 | FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |