Tri-GalNAc-NHS ester 是溶酶体靶向嵌合体 (LYTAC),也是 asialoglycoprotein receptor (ASGPR) 的配体。ASGPR 是一种在肝细胞上特异性表达的溶酶体靶向受体,用于降解包括膜蛋白在内的细胞外蛋白。Tri-GalNAc-NHS ester 可作为蛋白质降解剂,可用于 LYTAC的研究。
生物活性 | Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |