FAK ligand-Linker Conjugate 1 包含靶蛋白FAK配体和 PROTAC linker,可募集 E3 连接酶 (如 VHL,CRBN,MDM2 和 IAP 等类型)。FAK ligand-Linker Conjugate 1 可广泛用于 PROTAC 介导的蛋白降解。
| 生物活性 | FAKligand-Linker Conjugate 1 incorporates a ligand forFAK, and aPROTAClinker, which recruitE3 ligases(such as VHL, CRBN,MDM2, and IAP).FAKligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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