Myelin Basic Protein(87-99)(human,bovine,rat)(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
分子式 | C74H114N20O17•XCF3COOH |
分子量 | 1555.8 |
溶解度 | Water: 1 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Myelin basic protein (MPB) (87-99) is an encephalitogenic peptide. Active immunization with MBP (87-99) induces experimental autoimmune encephalomyelitis (EAE) in SJL/J mice and Lewis rats. It induces T cell and microglial activation and MHC class II expression in the spinal cord and decreases latency to paw withdrawal in response to mechanical and thermal stimuli in rats without inducing paralysis. Intranasal administration of MBP (87-99), alone or in combination with MBP (68-86), prior to immunization with guinea pig MBP (gp-MBP) confers protection against EAE induction in Lewis rats. |