3-epi-Vitamin D3 (Epicholecalciferol) (Compound 4) 是维生素 D3 类似物,是一种Hedgehog pathway抑制剂,在U87MG 细胞中测定的IC50为 39.2 μM。
生物活性 | 3-epi-Vitamin D3 (Epicholecalciferol) (Compound 4), a Vitamin D3 analogue, is aHedgehogpathwayinhibitor with anIC50of 39.2 μM measured in U87MG cells[1]. |
体外研究 (In Vitro) | 3-epi-Vitamin D3 (Epicholecalciferol) (5 or 10 μM) significantly upregulates Cyp24A1 in U87MG, HT-29 and C3H10T1/2 cells[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |