Ponsegromab (PF 06946860) 是一种有效的，选择性的人源化抗 GDF15 抗体抑制剂，具有抗恶病质活性。 Ponsegromab 与 GDF15 结合并阻止其与 GFRAL 结合，从而阻断 GDF15/GFRAL 介导的信号传导。 Ponsegromab 可用于癌症研究。
| 生物活性 | Ponsegromab (PF 06946860) is a potent and selective humanized anti-GDF15antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers[1]. |
| IC50& Target | |
| Clinical Trial | |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
