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Ganglioside GM2 Asialo Mixture
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ganglioside GM2 Asialo Mixture图片
CAS NO:35960-33-9
包装:100μg
市场价:9534元

Cas No.35960-33-9
别名神经节苷脂
Canonical SMILES[R]C(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@]2([H])O[C@H](CO)[C@H](O[C@@]3([H])[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)[C@H](O)[C@H]2O)[C@@H](CO)O1)=O
分子式C56H104N2O18(for stearoyl)
分子量1093.4
溶解度Chloroform:Methanol:Water (2:1:0.1): Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths.

 
 
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