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Isolimonexic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isolimonexic acid图片
CAS NO:73904-93-5

Isolimonexic acid 是从柠檬种子中分离得到的一种类柠檬酸,具有抗癌和抗芳香化酶 (anti-aromatase) (IC50=25.60 μM) 特性。
生物活性

Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer andanti-aromatase(IC50=25.60 μM) properties[1].

IC50& Target

IC50: 25.60 μM (aromatase)[1]

体外研究
(In Vitro)

Isolimonexic acid (200 μM; 72 hours) exhibits cytotoxicity on MCF-7 cells and shows no cytotoxicity against the MDA-MB-231 cell lines[1].
Isolimonexic acid (50 μg/ml; 48, 96 and 144 hours) exhibits cell growth inhibition of Panc-28 cells in a time-dependent manner.And it percent inhibition comparison to control cells are 21%, 68%, and 90.58% at 48, 72, and 144 h, respectively[2].

分子量

502.51

Formula

C26H30O10

CAS 号

73904-93-5

结构分类
  • Others
来源
  • Plants
  • Rutaceae
  • Citrus limon(L.) Burm. F.
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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