Taragarestrant (D-0502) meglumine 是一种有效的、具有口服活性的、选择性的雌激素受体 (estrogen receptor) 降解剂。Taragarestrant meglumine 在各种 ER+ 乳腺癌细胞系和移植模型中显示出强大的活性。
| 生物活性 | Taragarestrant (D-0502) meglumine is a potent, orally active and selectiveestrogen receptordegrader (SERD). Taragarestrant meglumine shows potent activity in various ER+ breastcancercell lines and xenograft models[1][2]. |
体内研究
(In Vivo) | Taragarestrant (D-0502) exhibits superior PK profiles suitable for clinical development[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
