SYM 2206 是一种有效的非竞争性 AMPA 受体拮抗剂，IC50 为 1.6 μM。
| Cas No. | 173952-44-8 |
| 别名 | 8-(4-氨基苯基)-5-甲基-N-丙基-1,3-二氧杂环戊烯并[4,5-G]酞嗪-6(5H)-甲酰胺 |
| 化学名 | (S)-8-(4-aminophenyl)-5-methyl-N-propyl-[1,3]dioxolo[4,5-g]phthalazine-6(5H)-carboxamide |
| Canonical SMILES | O=C(NCCC)N([C@@H](C)C1=C2)N=C(C(C=C3)=CC=C3N)C1=CC4=C2OCO4 |
| 分子式 | C20H22N4O3 |
| 分子量 | 366.42 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist. References:
[1]. Welch NC, et al. Traditional AMPA receptor antagonists partially block Na v1.6-mediated persistent current. Neuropharmacology. 2008 Dec;55(7):1165-71. |
