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SBE-β-CD
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SBE-β-CD图片
CAS NO:182410-00-0

磺丁基-β-环糊精
Sulfobutylether-β-Cyclodextrin
SBE-β-CD 是磺基丁基醚β-cyclodextrin衍生物,其用作赋形剂或助溶剂以增加难溶性药物的溶解度。
生物活性

SBE-β-CD is a sulfobutyletherβ-cyclodextrinderivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents[1].

体外研究
(In Vitro)

SBE-β-CD is a chemically modified β-CD that is a cyclic hydrophilic oligosaccharide which is negatively charged in aqueous media. β-CD functioned is a solubilizer only at low concentrations, whereas SBE7-β-CD exhibits strong solubilizing effects over a wide concentration range[1].

体内研究
(In Vivo)

20% SBE-β-CD in saline:
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
1. Dissolve 0.9 g of NaCl in 100 mL distilled water to make a clear 0.9% saline solution.
2. Measure 2 g of dry SBE-β-CD.
3. Dissolve 2 g of SBE-β-CD in 0.9% saline to make 10 mL with a 20% (w/v) concentration. These may require ultrasonic (20-40 kHz, 30 seconds, repeat 3 times) or heating (37℃ for about 30 minutes). If precipitation is observed, the precipitates can be dissolved by heating to 37℃ and vortexing before use.

分子量

2083-2257

性状

Solid

CAS 号

182410-00-0

中文名称

磺丁基-β-环糊精;磺丁基醚-β-环糊精

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

溶解性数据
In Vitro: 

H2O : 125 mg/mL(Need ultrasonic)

 
 
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