5,7-Dichlorokynurenic acid (5,7-DCKA) 是 NMDA 受体上甘氨酸位点的选择性竞争性拮抗剂,KB 为 65 nM。
Cas No. | 131123-76-7 |
别名 | 5,7-二氯犬尿喹啉酸; 5,7-DCKA |
化学名 | 5,7-dichloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid |
Canonical SMILES | ClC1=C2C(NC(C(O)=O)=CC2=O)=CC(Cl)=C1 |
分子式 | C10H5Cl2NO3 |
分子量 | 258.06 |
溶解度 | Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |