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Tramiprosate-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tramiprosate-d6图片
CAS NO:1131576-06-1

Homotaurine-d6
3-Amino-1-propanesulfonic acid-d6
Tramiprosate-d6 (Homotaurine-d6) 是 Tramiprosate 的氘代物。Tramiprosate (Homotaurine),一种具有口服活性和可透过血脑屏障的天然氨基酸,存在于各种红色海藻中。Tramiprosate 与可溶性 Aβ 结合并以非原纤维形式维持 Aβ。Tramiprosate 还是一种 GABA 类似物,具有神经保护,抗惊厥和抗高血压的作用。
生物活性

Tramiprosate-d6 (Homotaurine-d6) is the deuterium labeled Tramiprosate. Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of redmarine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

145.21

性状

Solid

Formula

C3H3D6NO3S

CAS 号

1131576-06-1

中文名称

高牛磺酸 d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month
溶解性数据
In Vitro: 

H2O : 50 mg/mL(344.33 mM;ultrasonic and warming and heat to 60℃)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM6.8866 mL34.4329 mL68.8658 mL
5 mM1.3773 mL6.8866 mL13.7732 mL
10 mM0.6887 mL3.4433 mL6.8866 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。

 
 
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