6-Phosphogluconic acid trisodium 是一种有效的,竞争性磷酸葡萄糖异构酶 (PGI) 抑制剂,对 6-磷酸葡萄糖和 6-磷酸果糖的Ki值分别为 48 μM 和 42 μM。6-Phosphogluconic acid trisodium 是一种内源性代谢物 (endogenous metabolite)。
生物活性 | 6-Phosphogluconic acid trisodium is a potent and competitivephosphoglucose isomerase (PGI)inhibitor withKis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is anendogenous metabolite[1][2]. |
IC50& Target | phosphoglucose isomerase[1] |
体外研究 (In Vitro) | 6-Phosphogluconic acid trisodium (0.5-2.0 mM) completely inhibits the activity of PGI with glucose 6-phosphate (0.05- 0.5 mM) as the substrate[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |