H-D-Abu-OH 是一种弱 GlyR(抑制性甘氨酸受体)和 PMBA 激动剂,GlyR 的 EC50 为 9 mM。
Cas No. | 338-69-2 |
别名 | D-丙氨酸; (R)-Alanine; Ba 2776; D-α-Alanine |
化学名 | (2S)-2-aminobutanoic acid |
Canonical SMILES | CCC(C(=O)O)N |
分子式 | C4H9NO2 |
分子量 | 103.1 |
溶解度 | Soluble in water or 1% acetic acid |
储存条件 | Desiccate at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR. References: [1]. Schmieden V, et al. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol Pharmacol. 1995 Nov;48(5):919-27. [2]. Saitoh T, et al. A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br J Pharmacol. 1994 Sep;113(1):165-70. |